Overview:

The research program at the Maria Fareri Children’s Hospital at Westchester Medical Center and New York Medical College consists of basic, translational and clinical research in cancer, hematological and blood disorders, immune diseases and stem cell transplantation. There is a multidisciplinary team that focuses on specific areas of research into hematological malignancies, solid tumors, hemoglobinopathies, immune deficiencies, bone marrow failures, hemostasis and thrombosis and other selected diseases. The program also affords a unique opportunity for students, residents, fellows and post doctoral candidates to pursue research and training in the above-mentioned fields. Several “state of the art” research programs include: cancer genetics, cancer biology, tumor immunology, transplantation biology and immunology, stem cell biology, hematopoiesis, stem cell regenerative therapy, developmental and experimental therapeutics, stem and cellular transplantation and others.

 

Diseases:

The research programs cover many areas of Hematology, Oncology and Stem Cell Transplantation including: acute and chronic leukemias, lymphomas, brain tumors, solid tumors (neuroblastoma, sarcomas, Wilms Tumor, hepatic and germ cell tumors), hemoglobinopathies (sickle cell disease and thalassemia), bone marrow failure syndromes (aplastic anemia and Fanconi anemia), immunodeficiencies (SCID and CGD), bleeding and clotting disorders (hemophilia, von Willebrand disease, idopathic thrombocytopenia etc.), and lymphohistiocytic disorders.

 

Key Team Members / Disciplines (Photo Gallery):

  • Director: Mitchell S. Cairo, MD
  • Basic Research Laboratory Manager: Janet Ayello, MS
  • Clinical Research Nurse Coordinator: Lauren Harrison, RN, MSN
  • Hematological Malignancies: Mitchell S. Cairo, MD and Jessica Hochberg, MD
  • Hemostasis/Thrombosis: Oya Tugal, MD
  • Brain Tumors: Michael Tobias, MD
  • Solid Tumors: Fevzi Ozkaynak, MD and Chitti Ramanamoorthy, MD
  • Sickle Cell Disease: Claudio Sandoval, MD and Cori Abikoff, MD
  • Immunodeficiencies: Cori Abikoff, MD and Subhadra Siegel, MD
  • Lymphohistiocytic Diseases: Oya Tugal, MD
  • Developmental and Experimental Therapeutics: Behzad Bidadi, MD
  • Stem and Cellular Therapy: Mitchell S. Cairo, MD
  • Cancer Biology: Wen Luo, PhD
  • Tumor Immunology: Aradhana Tiwari, PhD
  • Basic Immunology: Carl Hamby, PhD
  • Transplantation and Translational Immunology: Yaya Chu, PhD
  • Stem Cell Biology: Yanling Liao, PhD
  • Hematopoiesis: Janet Ayello, MS
  • Clinical Pharmacology: Liana Klejmont, PharmD
  • Biostatistics: Qiuhu Shi, PhD

 

 

Unique Features:

  • 2,500 square feet of wet laboratory space
  • IVIS small animal imaging core
  • Large and modern vivarium
  • Cellular and Tissue Engineering Laboratory (GMP Quality)
  • High Speed, Multisort, Sterile Flow Cytometer/Sorter
  • Strong and interactive collaborations with basic science department
  • 25 years of clinical and translational research experience
  • Multiple FDA IND/IDE’s
  • Experienced basic, translational and clinical research staff
  • COG Accredited
  • PBMTC Accredited
  • NMDP Accredited
  • Sickle Cell Disease Transplant Consortium (Lead Institution)
  • High Risk Leukemia Transplant consortium (Lead Institution)
  • Lymphoma Cell Therapy Consortium (Lead Institution)
  • Sarcoma Cell Therapy Consortium (Lead Institution)
  • Human Placenta-Derived Stem Cell Consortium (Lead Institution)