• Hepatoblastoma
    • AHEP0731 – Treatment of Children with All Stages of Hepatoblastoma with Temsirolimus (IND#122782, NSC#683864) Added to High Risk Stratum Treatment

 

 

  • Juvenile Myelomonocytic Leukemia
    • ASCT1221 – A Randomized Phase II Study Comparing Two Different Conditioning Regimens Prior to Allogeneic Hematopoietic Cell Transplantation (HCT) for Children with Juvenile Myelomonocytic Leukemia (JMML)
    • NYMC 504 – Allogeneic Stem Cell Transplantation Followed by Targeted Immune Therapy in Average Risk Myelogenous Leukemia/Myelodysplastic Syndrome/Juvenile Myelomonocytic Leukemia (AML/MDS/JMML)

 

  • Kidney Tumors
    • NYMC 165 – A Pilot Study to Evaluate the Safety and Preliminary Evidence of an Effect of ODSH (2-O, 3-O Desulfated Heparin) in Accelerating Platelet Recovery in Pediatric Patients With a Recurrent Solid Tumor Receiving “ICE” Chemotherapy (IND 122872)
    • AREN03B2 – Renal Tumors Biology Studies

 

 

  • Neuroblastoma
    • ANBL0032 – Phase III Randomized Study of Chimeric Antibody 14.18 (Ch14.18) in High Risk Neuroblastoma Following Myeloablative Therapy and Autologous Stem Cell Rescue.
    • ANBL1221 – A Phase II Randomized Trial of Irinotecan/Temozolomide with Temsirolimus (NSC# 683864, IND# 61010) or Chimeric 14.18 Antibody (ch14.18) (NSC# 623408, IND#4308) in Children with Refractory, Relapsed or Progressive Neuroblastoma
    • ANBL1232 – Utilizing Response & Biology-Based Risk Factors to Guide Therapy in Patients with Non-High Risk Neuroblastoma
    • ANBL00B1 – Neuroblastoma biology studies
    • NYMC 165 – A Pilot Study to Evaluate the Safety and Preliminary Evidence of an Effect of ODSH (2-O, 3-O Desulfated Heparin) in Accelerating Platelet Recovery in Pediatric Patients With a Recurrent Solid Tumor Receiving “ICE” Chemotherapy (IND 122872)

 

  • Non-Hodgkin Lymphoma (Burkitt, Large Cell, Lymphoblastic, Anaplastic)

 

 

 

 

  • Solid Tumors
    • A Study to Evaluate 5 μg/kg Tbo-filgrastim in Infants, Children and Adolescents With Solid Tumors Without Bone Marrow Involvement
    • D9902 – A COG Soft Tissue Sarcoma Diagnosis, Biology and Banking Protocol
    • NYMC 165 – A Pilot Study to Evaluate the Safety and Preliminary Evidence of an Effect of ODSH (2-O, 3-O Desulfated Heparin) in Accelerating Platelet Recovery in Pediatric Patients With a Recurrent Solid Tumor Receiving “ICE” Chemotherapy (IND 122872)
    • ARST1321 – Pazopanib Neoadjuvant Trial In Non-Rhabdomyosarcoma Soft Tissue Sarcomas (PAZNTIS): A Phase II/III Randomized Trial of Preoperative Chemoradiation or Preoperative Radiation Plus or Minus Pazopanib (NSC# 737754, IND# 118613)
    • A0ST06B1 – Osteosarcoma Biology Studies
    • AEWS07B1 – Ewing Sarcoma Biology Studies
    • AEWS1031 – A phase III randomized trial of adding vincristine – topotecan- cyclophosphamide to standard chemotherapy in initial treatment of non-metastatic Ewing sarcoma
    • AEWS1221 -Randomized phase II trial evaluating the addition of the IGF – 1R monoclonal antibody Ganitumab to multiagent chemotherapy for patients with newly diagnosed metastatic Ewing sarcoma

 

 

  • Wellness and Survivorship
    • NYMC 168 – Cancer and Blood Marrow Transplantation Wellness and Survivorship Research

 

  • Wilms Tumor
    • CCG4914L – National Wilms Tumor Late Effects Study